Opportunity Information: Apply for W81XWH 19 PRMRP IIRA

The CDMRP Peer Reviewed Medical Research Program (PRMRP) Investigator-Initiated Research Award (IIRA) is a Department of Defense funding opportunity meant to back investigator-driven medical research projects that can make a meaningful contribution to research and/or patient care for diseases or conditions that fall within at least one of the FY19 PRMRP Topic Areas. The central idea is to give researchers room to propose strong, original studies that are not limited to a narrow preset method, as long as the work is clearly connected to one or more of the designated PRMRP topic areas for that fiscal year.

A key expectation of this award is that the proposed research is built on a clear rationale supported by relevant evidence. That rationale can come from multiple sources, including laboratory findings, population-based or epidemiological observations, a clinician's direct experience treating patients, or other forms of preliminary or anecdotal insight that point to an important scientific or clinical question. Regardless of where the idea originates, the application must include data that justify the approach and demonstrate that the study is grounded in reality. Those supporting data can be unpublished preliminary results generated by the applicant or evidence drawn from the existing published literature, but they need to be clearly relevant to why the proposed study should be done and why it is likely to succeed.

The program places heavy emphasis on impact. The IIRA is positioned to support research that could generate highly impactful results capable of driving critical discoveries or major advances in the field. Applicants are expected to explain, in a straightforward and convincing way, what the project is likely to produce in both the near term and long term. These outcomes can include new knowledge (for example, better understanding of disease mechanisms, risk factors, biomarkers, or treatment responses) and/or materiel products (such as tools, datasets, methods, protocols, or other tangible research-enabling outputs). Just as important, the proposal must connect those anticipated outputs to a central, critical problem in the relevant research or patient-care landscape, showing how the study would move the field forward rather than simply adding incremental information.

Administratively, the opportunity is offered by the Department of Defense, Department of the Army, through the U.S. Army Medical Research Acquisition Activity (USAMRAA), under Funding Opportunity Number W81XWH 19 PRMRP IIRA. The assistance mechanisms listed include both grants and cooperative agreements, reflecting that awards may involve varying degrees of government involvement depending on the specific project. It is categorized under science and technology and other research and development, with CFDA number 12.420. Eligibility is described as unrestricted, meaning it is broadly open to many entity types, subject to any additional eligibility clarifications that may appear in the full announcement. The posting indicates an expected total of 42 awards, with an original closing date of July 11, 2019, and a creation date of January 15, 2019. The listed award ceiling is shown as 0, which typically signals that the maximum award amount is not captured in that summary field and would need to be confirmed in the full funding announcement or associated program guidance.

Overall, this award supports well-justified, investigator-originated biomedical research tied to FY19 PRMRP topic areas, with a strong requirement to show supporting evidence and a clear, credible path to outcomes that could substantially influence research directions and/or improve patient care.

  • The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "CDMRP Peer Reviewed Medical Research Program Investigator-Initiated Research Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on Jan 15, 2019.
  • Applicants must submit their applications by Jul 11, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 42 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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