Ryan White HIV/AIDS Program Part C Capacity Development Program | HRSA 25 049

Opportunity Information: Apply for HRSA 25 049

The Ryan White HIV/AIDS Program Part C Capacity Development Program (HRSA-25-049) is a discretionary federal grant opportunity from the Health Resources and Services Administration (HRSA) focused on helping organizations build stronger, more resilient systems for delivering HIV primary health care. The central goal is organizational capacity building, meaning the program is designed to help service providers adapt to a changing health care environment while improving access to high-quality HIV medical care for people who are low-income and underserved. In practical terms, this opportunity is aimed at strengthening the internal abilities of eligible organizations so they can sustain and improve HIV clinical services, respond to evolving policies and care models, and better meet the needs of people with HIV in their communities.

This funding opportunity falls under the Health activity category and is associated with CFDA number 93.918. It is authorized under Section 2652 of the Public Health Service (PHS) Act. HRSA expects to make around 60 awards under this notice of funding opportunity (NOFO). The listing shows an award ceiling of 0, which typically indicates that a specific maximum award amount is not provided in the summary field and applicants should rely on the full NOFO for detailed budget expectations, limits, and any standardized funding amounts or formulas that apply.

Eligibility is limited to domestic organizations and government entities. Eligible applicants include public entities and nonprofit private entities, including community-based organizations, as well as nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education in the categories listed). Government applicants may include state governments, county governments, city or township governments, and special district governments. Native American tribal governments (federally recognized) and Native American tribal organizations are also eligible. The term "domestic" is defined broadly to include the 50 states and the District of Columbia, the Commonwealth of Puerto Rico, the Northern Mariana Islands, American Samoa, Guam, the U.S. Virgin Islands, and the freely associated states and territories listed: the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau.

There are clear restrictions on who may not apply. Individuals are not eligible applicants under this NOFO. Foreign entities are not eligible for this award, which means organizations based outside the defined U.S. domestic jurisdictions cannot apply, even if they have partnerships or connections to U.S.-based programs. The opportunity was created on January 16, 2025, and the original application closing date is March 18, 2025.

Overall, the program is best understood as a targeted investment in the operational and service-delivery strength of Ryan White Part C-related HIV primary care providers and similar eligible organizations. The intent is not only to support direct care access for underserved people with HIV, but also to ensure that the organizations providing that care have the systems, staffing capacity, and readiness needed to keep pace with changes in the broader health care landscape while maintaining high-quality HIV clinical services.

• The Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Ryan White HIV/AIDS Program Part C Capacity Development Program" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.918.
• This funding opportunity was created on 2025-01-16.
• Applicants must submit their applications by 2025-03-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• The number of recipients for this funding is limited to 60 candidate(s).
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Others.

Apply for HRSA 25 049

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