Opportunity Information: Apply for RFA PS 21 001

The Minority HIV Research Initiative (MARI) funding opportunity (RFA PS 21 001) is a CDC-led cooperative agreement designed to advance HIV-related epidemiologic and implementation science research in racial and ethnic minority communities that experience a disproportionate burden of HIV. At the same time, the program is explicitly structured to build and strengthen research capacity among investigators who are historically underrepresented in research and who are working in or closely with the communities most affected. The overall intent is to generate practical, high-impact evidence that can improve public health outcomes while also expanding the pipeline and support structure for minority investigators conducting HIV research.

This NOFO sits within the Department of Health and Human Services, Centers for Disease Control and Prevention, and aligns with CDC goals to promote health and reduce disease and disability. The emphasis on epidemiology signals support for work that helps describe and explain HIV patterns, drivers, and disparities in real-world settings, including factors that influence risk, testing, prevention uptake, and care outcomes. The emphasis on implementation science signals an interest in studies that look at how evidence-based HIV prevention and care strategies are actually adopted, delivered, and sustained in community and clinical settings, especially where structural barriers, resource limitations, stigma, and inequities affect access and quality. In practical terms, the opportunity is aimed at research that can move beyond documenting disparities to identifying and testing approaches that improve delivery, reach, and effectiveness of HIV-related interventions in minority communities.

The award mechanism is a cooperative agreement, which generally means applicants should expect substantial involvement from CDC during the project period compared with a standard grant. Cooperative agreements commonly include collaboration, technical assistance, shared learning, or coordination activities, and they often prioritize projects that can translate findings into actionable public health practice. The NOFO is categorized as discretionary funding in the health activity category, with CFDA numbers 93.941 and 93.943. The stated award ceiling is $350,000, and CDC anticipated making about 10 awards under this announcement, suggesting a competitive opportunity with a moderate level of funding intended to support focused research projects and capacity-building activities rather than large multi-site clinical trials.

Eligibility is broad and includes many organization types that could plausibly support community-engaged HIV research and mentorship-based capacity building. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education in those categories); as well as for-profit organizations (other than small businesses) and small businesses. This wide eligibility reflects an intention to allow applications from academic institutions, community-based organizations, public health departments, tribal entities, and other groups that have established relationships with priority communities and the practical ability to conduct applied research.

Key administrative details include the posting timeframe and submission deadline: the opportunity was created on August 12, 2020, with an original closing date of October 14, 2020. Applications were required to be submitted electronically by 5:00 p.m. Eastern Time on the due date. While those dates indicate the original competition window, the program description provides a clear picture of the types of projects CDC intended to support: research that is both scientifically rigorous and rooted in the realities of minority communities disproportionately affected by HIV, paired with deliberate efforts to strengthen investigator capacity and long-term research infrastructure in those communities.

  • The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Minority HIV Research Initiative (MARI) to Support Epidemiologic and Implementation Science Research in Racial/Ethnic Minority Communities Disproportionately Affected by HIV and Build Research Capacity Among Historically Underrepresented Researchers" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.941, 93.943.
  • This funding opportunity was created on Aug 12, 2020.
  • Applicants must submit their applications by Oct 14, 2020 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $350,000.00 in funding.
  • The number of recipients for this funding is limited to 10 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses.
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