Opportunity Information: Apply for RFA RM 23 012
The Community Partnerships to Advance Science for Society (ComPASS): Health Equity Research Hubs (UC2 Clinical Trial Optional) funding opportunity (RFA-RM-23-012) is a National Institutes of Health (NIH) Notice of Funding Opportunity designed to establish a set of Health Equity Research Hubs that will function as shared research and support centers for a larger ComPASS program portfolio. The core idea is that community-led projects focused on health equity and structural change often need strong, practical research infrastructure behind them to be successful, credible, and sustainable. These Hubs are meant to provide that backbone by offering high-quality scientific and technical support while staying grounded in authentic community engagement and community priorities.
Within the broader ComPASS Program, the Hubs are one of three connected components working together. First are the community-led health equity structural intervention (CHESI) projects, which are the on-the-ground efforts led with and by communities to address social determinants of health (SDOH) and structural drivers of inequity. Second is the ComPASS Coordination Center, which is expected to help align activities across the program, facilitate communication, and support cross-project learning. Third are these Health Equity Research Hubs, which are intended to serve as centralized research resources assigned to support specific CHESI projects. In practice, that means a Hub is not simply running its own standalone research agenda; it is being funded to actively strengthen and accelerate the community-led CHESI work by bringing specialized expertise, tools, and training that communities and local partners may not otherwise be able to access easily.
The purpose of the Hubs is described in very applied terms: provide tailored scientific, technical, and collaborative support that helps CHESI projects succeed. This includes supporting sustainable community engagement (so partnerships are not extractive or short-lived), strengthening local and project-level research capacity (so communities can more fully participate in, shape, and benefit from the research process), and delivering training (so project teams gain skills in areas like data collection, evaluation, implementation approaches, dissemination, and other research capabilities). The emphasis on tailoring is important: the Hub model suggests support should be matched to the unique needs, context, and readiness of each assigned CHESI project rather than forcing every project into one standardized approach.
Thematically, the Hubs are tied directly to improving health outcomes by addressing SDOH and structural factors. In other words, the work is not limited to individual behavior change or clinical care improvements alone; it is meant to support interventions that tackle upstream conditions shaping health and inequities, such as housing stability, access to nutritious food, transportation, education, economic opportunity, environmental exposures, discrimination, policy environments, and other structural barriers. The Hubs are positioned as key enablers of rigorous, community-engaged research and evaluation around these types of structural interventions, which can be complex to measure and often require interdisciplinary methods and strong partnership governance.
From an administrative and funding standpoint, this opportunity uses a cooperative agreement mechanism (UC2), which generally signals substantial federal involvement compared to a standard grant. In many NIH programs, cooperative agreements mean the NIH will have an active partnership role in shaping certain aspects of the work, coordination expectations, or program-wide collaboration. The listing also indicates "Clinical Trial Optional," meaning applicants may propose clinical trial activities if they are appropriate to the Hub-supported work, but a clinical trial is not required. The activity category is Health, and the CFDA (now commonly referred to as Assistance Listing) number provided is 93.310.
Eligibility is broad and includes many types of U.S.-based entities that could credibly serve as a research and support hub, spanning government, education, nonprofit, and private-sector organizations. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities/Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; small businesses; and other eligible organizations. The NOFO also highlights additional eligible applicant types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. This breadth aligns with the program's goal of meeting communities where they are and allowing many different kinds of institutions to serve as credible, community-responsive research partners.
At the same time, the opportunity is clear about limits related to foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply. Non-domestic components of U.S. organizations are also not eligible to apply. In addition, foreign components as defined by the NIH Grants Policy Statement are not allowed. These restrictions mean applicants must structure the Hub and its supported activities as entirely domestic efforts under NIH policy, without formal foreign components.
Key logistical details in the source information include the agency (NIH), the funding opportunity number (RFA-RM-23-012), the posting/creation date (2023-08-24), and the original application closing date (2023-10-31). The award ceiling and expected number of awards are not specified in the provided excerpt, which typically means applicants would need to consult the full NOFO text or related NIH documentation to confirm budgets, project periods, and the number of anticipated Hub awards.
Overall, the ComPASS Health Equity Research Hubs opportunity is best understood as funding for institutions that can act as high-capacity, community-engaged research support centers for multiple community-led structural intervention projects. The Hubs are expected to strengthen the quality, rigor, and real-world usefulness of health equity work by helping CHESI projects design and evaluate interventions addressing upstream drivers of inequities, build local research capacity, and sustain community partnerships over time, all while operating in close coordination with the other ComPASS program components.Apply for RFA RM 23 012
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Community Partnerships to Advance Science for Society (ComPASS): Health Equity Research Hubs (UC2 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310.
- This funding opportunity was created on 2023-08-24.
- Applicants must submit their applications by 2023-10-31. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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