Opportunity Information: Apply for HRSA 19 040
Capacity Building in the Ryan White HIV/AIDS Program to Support Innovative Program Model Replication (HRSA-19-040) is a three-year Special Projects of National Significance (SPNS) cooperative agreement funded by the Health Resources and Services Administration (HRSA) within the U.S. Department of Health and Human Services. The opportunity is framed around a practical problem in the current HIV landscape: as the epidemic changes, Ryan White HIV/AIDS Program (RWHAP) systems need faster, more reliable ways to adopt interventions that are already showing real-world success, especially in places where HIV burden and inequities remain high. Rather than asking applicants to invent brand-new interventions, the core intent is to help RWHAP recipients and subrecipients build the skills, infrastructure, and confidence to take existing evidence-informed models and replicate or adapt them effectively.
A central theme of the NOFO is replication of proven approaches. Over the past several years, many RWHAP-funded providers and partners have developed innovative interventions that improved outcomes along the HIV care continuum, and many of those programs have documented what they did through replication manuals, toolkits, and other implementation resources. HRSA is signaling that these materials should not sit on a shelf; they should be used to bring effective practices to scale. The grant therefore emphasizes capacity building so that organizations can select appropriate models, understand what makes them work, adapt them without losing their essential components, and integrate them into local systems of care.
The initiative places particular focus on RWHAP jurisdictions that are disproportionately affected by HIV. In practice, this means HRSA wants the project to help high-need communities and systems strengthen their ability to implement comprehensive, high-quality, culturally competent HIV screening, care, and treatment services, including both medical care and the support services that help people access and stay in care. The target population includes people living with HIV who are not engaged in care, not fully engaged, or at risk of falling out of care, since these gaps drive poorer health outcomes and fuel disparities across the continuum.
HRSA outlines several expected outcomes that collectively describe what success should look like. One major outcome is stronger facility among RWHAP recipients and subrecipients in the targeted jurisdictions to use and integrate innovative service models, tools, interventions, and replication manuals in ways that align with RWHAP rules. The NOFO explicitly points applicants to the allowable service categories described in Policy Clarification Notice 16-02 (Eligible Individuals and Allowable Uses of Funds), reinforcing that innovation and replication still need to fit within RWHAP program requirements. Another expected result is increased awareness and practical knowledge among participating organizations about why evidence-informed interventions are valuable, what is available through the RWHAP repository of innovative interventions, how replication and adoption typically work, what implementation challenges are likely to arise, and what resources exist to address those challenges.
Beyond staff-level learning, HRSA is looking for system-level capacity gains. The opportunity aims to strengthen organizational and cross-partner systems so that evidence-informed interventions can be adopted and sustained in real operating environments, not just piloted. That includes building the ability to deliver coordinated and culturally competent services that improve linkage to care, re-engagement, retention, access, and viral suppression. HRSA also anticipates the project will increase the RWHAP-wide capacity to disseminate innovative interventions more broadly, meaning the work should generate lessons, products, or processes that help others implement similar models. Ultimately, the program is designed to reduce disparities for people living with HIV, particularly disparities reflected in who gets linked to care, who stays in care, and who achieves viral load suppression.
Structurally, the funding mechanism is a cooperative agreement, which typically indicates substantial involvement by HRSA in guiding or partnering on key components of the project compared to a standard grant. The NOFO lists one expected award, and the award ceiling is shown as 0 in the source data (often a placeholder in listings that requires applicants to review the full announcement for budget expectations and limits). The opportunity is categorized as discretionary funding under the health activity category (CFDA 93.928). Eligibility is listed as "Others (see text field entitled Additional Information on Eligibility for clarification)," which is a reminder that interested applicants would need to consult the full NOFO language to confirm applicant type requirements and any program-specific conditions.
Finally, HRSA positions this SPNS initiative as complementary to another HRSA effort, HRSA-19-030, the Ryan White HIV/AIDS Program Access, Care, and Engagement Technical Assistance (ACE TA) Center. The ACE TA Center focuses on helping recipients and subrecipients enroll and engage people living with HIV in expanded coverage and on maintaining RWHAP as the payer of last resort. In contrast, HRSA-19-040 is focused on spreading and scaling innovative program models through replication capacity. Taken together, the two efforts reflect a broader strategy: strengthen the financing and coverage navigation side through technical assistance, while simultaneously accelerating the uptake of proven service delivery approaches that improve outcomes and narrow persistent inequities across the HIV care continuum.Apply for HRSA 19 040
- The Department of Health and Human Services, Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Capacity Building in the Ryan White HIV/AIDS Program to Support Innovative Program Model Replication" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.928.
- This funding opportunity was created on Nov 26, 2018.
- Applicants must submit their applications by Feb 25, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs)
What is HRSA-19-040?
HRSA-19-040, titled "Capacity Building in the Ryan White HIV/AIDS Program to Support Innovative Program Model Replication," is a three-year Special Projects of National Significance (SPNS) cooperative agreement funded by the Health Resources and Services Administration (HRSA) within the U.S. Department of Health and Human Services.
What problem is this funding opportunity trying to solve?
The opportunity is designed to address a practical challenge in today’s HIV landscape: as the epidemic changes, Ryan White HIV/AIDS Program (RWHAP) systems need faster, more reliable ways to adopt interventions that are already working in real-world settings, especially in communities with high HIV burden and persistent inequities.
Is this grant meant to create brand-new HIV interventions?
No. The core intent is not to invent new interventions. Instead, the focus is on helping RWHAP recipients and subrecipients build the skills, infrastructure, and confidence to replicate or thoughtfully adapt existing evidence-informed models that have already demonstrated success.
What does "replication" mean in the context of this NOFO?
Replication refers to taking proven, evidence-informed approaches (including interventions documented through replication manuals, toolkits, and other implementation resources) and implementing them in additional settings. The emphasis is on bringing effective practices to scale rather than leaving them unused.
Why does HRSA emphasize replication manuals and toolkits?
HRSA highlights that many RWHAP-funded organizations have already developed interventions that improved outcomes along the HIV care continuum and have documented those interventions in practical materials like manuals and toolkits. This opportunity signals that those resources should be actively used to expand successful practices into other jurisdictions and systems of care.
What kinds of capacity building does the opportunity emphasize?
The initiative emphasizes building organizational capacity to select appropriate models, understand what makes them effective, adapt them without losing essential components, and integrate them into local HIV systems of care in ways that are sustainable.
Which communities or jurisdictions are prioritized?
The NOFO places particular focus on RWHAP jurisdictions that are disproportionately affected by HIV. In practical terms, the project is expected to support high-need communities and systems where HIV burden and inequities remain high.
Who is the target population for the work supported by this grant?
The target population includes people living with HIV who are not engaged in care, not fully engaged in care, or at risk of falling out of care. These gaps contribute to poorer health outcomes and widen disparities across the HIV care continuum.
What types of services are in scope?
The opportunity references comprehensive, high-quality, culturally competent HIV screening, care, and treatment services, including both medical care and support services that help people access and stay in care.
What outcomes does HRSA expect from this project?
Expected outcomes include stronger ability among RWHAP recipients and subrecipients in targeted jurisdictions to use and integrate innovative service models and replication resources; increased awareness and practical knowledge about evidence-informed interventions and the replication process; improved system-level capacity to adopt and sustain interventions; and progress toward improved linkage, re-engagement, retention, access, and viral suppression, with an overall goal of reducing disparities.
How does HRSA expect organizations to choose and use interventions?
The NOFO describes a need for organizations to identify appropriate evidence-informed models, understand core components that drive effectiveness, anticipate implementation challenges, and use available resources to address those challenges while integrating the intervention into real operating environments.
What is the role of cultural competence in this initiative?
Cultural competence is explicitly emphasized. The project aims to strengthen the ability of organizations and partner systems to deliver coordinated, culturally competent services that improve engagement across the HIV care continuum and reduce disparities.
Does HRSA expect work that can benefit the broader RWHAP beyond the participating sites?
Yes. HRSA anticipates increased RWHAP-wide capacity to disseminate innovative interventions more broadly. That means the work should generate lessons, products, or processes that can help other organizations implement similar models.
What does it mean that this is a "cooperative agreement"?
A cooperative agreement typically indicates substantial involvement by HRSA in guiding or partnering on key components of the project, compared to a standard grant. In other words, HRSA is generally expected to play a more active role during the project period.
How long is the project period?
The project is described as a three-year SPNS cooperative agreement.
How many awards does HRSA expect to make?
The NOFO lists one expected award.
What is the maximum award amount?
The award ceiling is shown as 0 in the source listing, which is often used as a placeholder. Applicants are expected to review the full announcement for complete budget expectations and any funding limits.
What is the CFDA number and funding category for this opportunity?
The opportunity is categorized as discretionary funding under the health activity category, with CFDA 93.928.
Who is eligible to apply?
Eligibility is listed as "Others (see text field entitled Additional Information on Eligibility for clarification)." This indicates applicants need to consult the full NOFO language to confirm who can apply and whether any program-specific eligibility conditions apply.
How does HRSA-19-040 relate to the ACE TA Center (HRSA-19-030)?
HRSA describes this SPNS initiative as complementary to HRSA-19-030, the Ryan White HIV/AIDS Program Access, Care, and Engagement Technical Assistance (ACE TA) Center. The ACE TA Center focuses on helping recipients and subrecipients enroll and engage people living with HIV in expanded coverage and on maintaining RWHAP as the payer of last resort, while HRSA-19-040 focuses on spreading and scaling innovative program models through replication capacity.
What is the "payer of last resort" connection mentioned in the description?
The payer-of-last-resort concept is discussed in relation to the separate ACE TA Center effort (HRSA-19-030). HRSA-19-040 is positioned as complementary, focusing on replication capacity rather than coverage navigation, but the two efforts together reflect a broader strategy to strengthen both financing/coverage support and the uptake of proven service delivery approaches.
What is Policy Clarification Notice (PCN) 16-02 and why is it mentioned?
The NOFO explicitly points applicants to the allowable service categories described in Policy Clarification Notice 16-02 (Eligible Individuals and Allowable Uses of Funds). This reinforces that even when replicating or adapting innovative approaches, activities still need to align with RWHAP program rules and allowable uses of funds.
Where are evidence-informed interventions expected to come from?
The description references the RWHAP repository of innovative interventions and notes that many interventions have been documented through replication manuals, toolkits, and other resources created by RWHAP-funded providers and partners.
What kinds of implementation challenges is the project expected to address?
The NOFO anticipates that organizations will face common implementation challenges when adopting or adapting interventions and expects increased practical knowledge about what those challenges are likely to be and what resources exist to address them.
How does this opportunity connect to reducing HIV-related disparities?
The ultimate intent is to reduce disparities for people living with HIV, particularly disparities in linkage to care, retention in care, and achieving viral load suppression. The emphasis on high-burden jurisdictions and culturally competent, coordinated services is part of that equity focus.
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