Opportunity Information: Apply for PA 18 680
The grant opportunity titled "Administrative Supplement for the NIBIB Research Education Programs for Residents and Clinical Fellows (Admin Supp Clinical Trial Not Allowed)" (Funding Opportunity Number PA-18-680) is an NIH discretionary grant mechanism designed specifically to provide administrative supplement funding to existing awards under two earlier program announcements: PAR-12-085 and PAR-15-167, which support the NIBIB Research Education Programs for Residents and Clinical Fellows. In practical terms, this is not a standalone funding program for brand-new projects; it is a way for current, eligible NIBIB-supported research education programs to request additional funds to expand, enhance, or otherwise strengthen activities that are already supported under those parent awards. The administering agency is the National Institutes of Health, and the opportunity falls under a health-related funding activity category (CFDA 93.286), reflecting NIBIB's mission area within biomedical imaging and bioengineering.
A central feature of this administrative supplement announcement is its clinical trial restriction. Appointed trainees (residents and clinical fellows supported through the supplement) are not permitted to lead an independent clinical trial, meaning they cannot serve as the person responsible for initiating and directing a trial as the main driver. However, the FOA does allow trainees to gain meaningful research experience in the context of a clinical trial as long as the trial is led by an appropriate mentor or co-mentor. This structure preserves hands-on exposure to clinical trial research while keeping the formal trial leadership and regulatory responsibility with experienced investigators. For programs training residents and fellows, the intent is typically to build research skills, familiarity with clinical research methods, and exposure to translational work without placing early-stage trainees in the role of independent trial leaders.
Eligibility is limited and notably excludes foreign involvement. The opportunity lists eligible applicants as public and state-controlled institutions of higher education, and it explicitly states that non-U.S. entities are not eligible to apply. It also bars non-domestic components of U.S. organizations and does not allow foreign components as defined by the NIH Grants Policy Statement. In effect, the supplement request must be managed entirely within eligible U.S.-based institutions and activities, with no foreign institutional applicants or foreign project components included. The announcement also notes that applicants should consult the full funding announcement for detailed eligibility requirements, which is standard for NIH opportunities where institutional and programmatic nuances can matter.
From an administrative standpoint, the opportunity was created on February 23, 2018, and it listed an original closing date of June 17, 2020. The provided source data does not specify an award ceiling or expected number of awards, which is common for administrative supplement FOAs because supplement amounts and volumes often depend on availability of funds, the size and scope of the parent award, and NIH program priorities at the time of submission. Overall, the opportunity is best understood as a targeted mechanism for existing NIBIB resident and clinical fellow research education awardees to request incremental support, with clear boundaries around clinical trial leadership by trainees and strict limitations against foreign applicants or foreign components.Apply for PA 18 680
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Administrative Supplement for the NIBIB Research Education Programs for Residents and Clinical Fellows (Admin Supp Clilnical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.286.
- This funding opportunity was created on 2018-02-23.
- Applicants must submit their applications by 2020-06-17. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education.
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Frequently Asked Questions (FAQs)
1) What is the title of this grant opportunity?
The opportunity is titled "Administrative Supplement for the NIBIB Research Education Programs for Residents and Clinical Fellows (Admin Supp Clinical Trial Not Allowed)."
2) What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PA-18-680.
3) What type of funding is this (standalone grant or supplement)?
This is an NIH administrative supplement opportunity. It is not a standalone funding program for brand-new projects. It is intended for eligible, existing awards to request additional funds to expand, enhance, or strengthen activities already supported under the parent award.
4) Which existing (parent) awards can request this administrative supplement?
This supplement is designed specifically for existing awards made under two earlier program announcements: PAR-12-085 and PAR-15-167, which support the NIBIB Research Education Programs for Residents and Clinical Fellows.
5) Who is the administering agency?
The administering agency is the National Institutes of Health (NIH).
6) Which NIH mission area does this relate to?
The opportunity aligns with the National Institute of Biomedical Imaging and Bioengineering (NIBIB) mission area, within biomedical imaging and bioengineering.
7) What is the CFDA number and what does it indicate?
The opportunity is listed under CFDA 93.286. This reflects that it falls within a health-related NIH funding activity category associated with NIBIB's area of work.
8) Who are the intended trainees supported by this supplement?
The supplement is intended to support trainees who are residents and clinical fellows within NIBIB-supported research education programs.
9) Are clinical trials allowed under this supplement?
The announcement includes a clinical trial restriction described as "Clinical Trial Not Allowed" for trainees in terms of independent leadership. Trainees supported through the supplement are not permitted to lead an independent clinical trial.
10) What does "trainees cannot lead an independent clinical trial" mean in practice?
It means appointed trainees (residents and clinical fellows supported through the supplement) cannot serve as the person responsible for initiating and directing a clinical trial as the main driver. In other words, the trainee cannot be the independent trial leader with primary responsibility for the trial.
11) Can trainees still get experience working on clinical trials?
Yes. The FOA allows trainees to gain meaningful research experience in the context of a clinical trial as long as the trial is led by an appropriate mentor or co-mentor. This keeps formal trial leadership and regulatory responsibility with experienced investigators while still giving trainees hands-on exposure.
12) What is the main purpose of this administrative supplement?
The purpose is to provide additional funding to existing, eligible NIBIB-supported research education programs so they can expand, enhance, or otherwise strengthen activities already supported under the parent awards.
13) Who is eligible to apply (institution types)?
Eligible applicants include public and state-controlled institutions of higher education, as listed in the opportunity information provided.
14) Are non-U.S. (foreign) institutions eligible to apply?
No. The opportunity explicitly states that non-U.S. entities are not eligible to apply.
15) Are foreign components or non-domestic components allowed as part of a U.S. applicant's project?
No. The opportunity bars non-domestic components of U.S. organizations and does not allow foreign components as defined by the NIH Grants Policy Statement. The supplement request must be managed entirely within eligible U.S.-based institutions and activities, with no foreign project components included.
16) Does this FOA provide an award ceiling (maximum award amount)?
The provided information does not specify an award ceiling.
17) Does this FOA state how many awards NIH expects to make?
The provided information does not state an expected number of awards.
18) Why might award amounts and award volume not be listed for this type of opportunity?
Administrative supplement opportunities commonly do not list a fixed award ceiling or expected number of awards because supplement amounts and volume may depend on availability of funds, the size and scope of the parent award, and NIH program priorities at the time of submission.
19) When was this opportunity created?
The opportunity was created on February 23, 2018.
20) What was the original closing date listed for this opportunity?
The original closing date listed was June 17, 2020.
21) Is it important to review the full funding announcement for details?
Yes. The opportunity notes that applicants should consult the full funding announcement for detailed eligibility requirements, which can matter for NIH opportunities where institutional and programmatic nuances apply.
22) What is the overall takeaway on who should consider this supplement?
This is a targeted mechanism for existing NIBIB resident and clinical fellow research education awardees under PAR-12-085 or PAR-15-167 to request incremental support, with clear restrictions that trainees cannot independently lead clinical trials and with strict limitations against foreign applicants or foreign components.
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| Methods Development in Natural Products Chemistry (R41/R42 Clinical Trial Not Allowed) Apply for PA 18 682 Funding Number: PA 18 682 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics (R33 Clinical Trial Required) Apply for PAR 18 684 Funding Number: PAR 18 684 Agency: National Institutes of Health Category: Health Funding Amount: $1,515,000 |
| NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics (R61/R33 Clinical Trial Required) Apply for PAR 18 683 Funding Number: PAR 18 683 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NINDS Postdoctoral Mentored Career Development Award (K01 No Independent Clinical Trial Allowed) Apply for PAR 18 686 Funding Number: PAR 18 686 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NINDS Postdoctoral Mentored Career Development Award (K01 Clinical Trial Required) Apply for PAR 18 685 Funding Number: PAR 18 685 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Limited Competition : HIV/AIDS-related Non-Human Primate Animal Research Facilities Restoration Program in the Aftermath of Hurricane Maria (C06 Clinical Trial Not Allowed) Apply for PAR 18 693 Funding Number: PAR 18 693 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| USAID/Kyrgyz Republic Tuberculosis (TB) Control Program Apply for RFI 72011519RFA00001 Funding Number: RFI 72011519RFA00001 Agency: Kazakhstan USAID-Almaty Category: Health Funding Amount: Case Dependent |
| Center without Walls for PET Ligand Development for Alzheimer's disease related dementias (ADRDs) (U19 Clinical Trial Optional) Apply for RFA NS 18 025 Funding Number: RFA NS 18 025 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Interdisciplinary Research Teams to Investigate Reciprocal Basic Behavioral and Social Linkages Between Sleep and Stress (R24 Clinical Trial Optional) Apply for PAR 18 694 Funding Number: PAR 18 694 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3 Clinical Trial Required) Apply for PAR 18 696 Funding Number: PAR 18 696 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Basic and Translational Oral Health Research Related to HIV/AIDS (R01 Clinical Trial Not Allowed) Apply for PA 18 699 Funding Number: PA 18 699 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers (P50 Clinical Trial Optional) Apply for PAR 18 701 Funding Number: PAR 18 701 Agency: National Institutes of Health Category: Health Funding Amount: $1,000,000 |
| Natural Product, Multi-Site, Clinical Trial, Data Coordinating Center (Collaborative U24 - Clinical Trial Required) Apply for PAR 18 697 Funding Number: PAR 18 697 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Stimulating T4 Implementation Research to Optimize Integration of Proven-effective Interventions for Heart, Lung, and Blood Diseases and Sleep Disorders into Practice (STIMULATE) (R01 Clinical Trial Not Allowed) Apply for RFA HL 19 014 Funding Number: RFA HL 19 014 Agency: National Institutes of Health Category: Health Funding Amount: $485,000 |
| Basic and Translational Oral Health Research Related to HIV/AIDS (R21 Clinical Trial Not Allowed) Apply for PA 18 695 Funding Number: PA 18 695 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32) (Clinical Trials Not Allowed) Apply for PA 18 700 Funding Number: PA 18 700 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NEI Translational Research Program (TRP) on Therapy for Visual Disorders (R24 Clinical Trial Optional) Apply for PAR 18 707 Funding Number: PAR 18 707 Agency: National Institutes of Health Category: Health Funding Amount: $1,500,000 |
| Selective Cell and Network Vulnerability in Aging and Alzheimers Disease (R01 - Clinical Trial Not Allowed) Apply for PAR 18 706 Funding Number: PAR 18 706 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Autoimmunity Centers of Excellence, Basic Research Program (U19 Clinical Trial Not Allowed) Apply for RFA AI 18 002 Funding Number: RFA AI 18 002 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Autoimmunity Centers of Excellence, Clinical Research Program (UM1 Clinical Trial Required) Apply for RFA AI 18 003 Funding Number: RFA AI 18 003 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
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